Research brief · Metabolic health
Retatrutide: The Trial Results Are Real. The Online Certainty Is Not.
Verified phase-2/3 trial results, the results-published-nowhere gap, and what online certainty about the triple agonist runs ahead of.
Research archive · Issue by issue
Every claim leaves a trail.
Research briefs, quick reviews, and methodology notes—organized chronologically and labeled by evidence type.
Research brief · Metabolic health
Research brief · Precision Protocols
The Wolverine Stack: BPC-157 + TB-500 Under Audit
Widely used. Not yet tested. A claim-level audit of the stack across 38 verified sources — TB-500 identity, product quality, and the human-evidence gap.
Research brief · Cognitive health
The COSMOS Multivitamin Trial: What It Found and What It Didn't
21,442 participants. Two primary endpoints, both null. Three cognitive substudies with a small positive signal. What the evidence actually supports.
Research brief · Nutrition
Time-Restricted Eating & Intermittent Fasting: What the Evidence Actually Shows
Human trials, mechanisms, individual variation, and the honest limits of what fasting research can claim.
Research note · Glycemic control
Bergamot vs Metformin: What the Evidence Actually Shows
Three mechanisms (AMPK, GLP-1R, GLUT-4), 110 patients, zero head-to-head trials. Bergamot's multi-pathway activity is genuinely interesting — but the gap between mechanism and efficacy is wide.
Research brief · Longevity
BPC-157: What 30 Years of Preclinical Evidence Actually Shows
A close reading of the mechanisms, the animal evidence, and the human-data gap.
Methodology note · Practice
How we review evidence
Our editorial standards, search methodology, evidence-grading rubric, and conflicts-of-interest policy.